October 2024
Semaglutide for Weight Loss: How It Works and Getting Started
In the ever-evolving world of weight loss, semaglutide has become a game-changer. Originally developed as a treatment for type 2 diabetes, it is now gaining recognition for its effectiveness in helping people lose weight. Recently, semaglutide was approved by the FDA for medical weight loss under the brand names Wegovy® and Ozempic®, offering a new option for those struggling with weight management.
One of the primary focuses of Dr. Burns’ practice is breast and body contouring. Many of our patients present with specific weight-related goals. Plastic surgery is most effective when performed at a safe and stable weight. For this reason, we encourage our patients to achieve a body mass index (BMI) of less than 35, and if possible, less than 30. For many, diet and exercise alone are insufficient to reach these metrics. For such patients, semaglutide medical weight loss may be the best solution. We aim to provide all our patients with the opportunity to achieve their weight loss goals.
In this blog, we'll explore how semaglutide works, who is a good candidate for the treatment, and how to get started on your weight loss journey with this medication.
How Does Semaglutide Work for Weight Loss?
Semaglutide is a GLP-1 receptor agonist (glucagon-like peptide-1), which mimics a hormone naturally produced in the body. GLP-1 helps regulate blood sugar levels, and when used for weight loss, it also influences the brain's appetite centers. Here's how it works:
Appetite Suppression
Semaglutide targets areas of the brain that control appetite, helping people feel fuller with less food. This reduces overall calorie intake, a crucial factor in successful weight loss.
Slows Gastric Emptying
Semaglutide slows the process of gastric emptying, meaning food stays in the stomach longer. This contributes to a feeling of fullness, making it easier to adhere to a reduced-calorie diet.
Improves Insulin Sensitivity
Originally developed for diabetes, semaglutide has a beneficial effect on blood sugar regulation. Even in non-diabetics, improved insulin sensitivity can help prevent weight gain and promote fat loss, particularly around the abdomen.
Targets Excess Fat
While semaglutide helps reduce appetite and food intake, studies show that it specifically aids in the loss of body fat rather than just overall weight. This results in a more significant reduction in visceral fat, which is associated with health risks like heart disease and type 2 diabetes.
Who Is a Good Candidate for Semaglutide Weight Loss?
Semaglutide is designed for adults who struggle with obesity or are overweight and meet certain criteria. Here’s who might benefit the most from this medication:
1. BMI Consideration
Obese individuals:
Those with a BMI of 30 or higher are prime candidates.
Overweight Individuals:
People with a BMI of 27 or higher, especially if they also have weight-related conditions like high blood pressure, type 2 diabetes, or high cholesterol.
2. People with Weight-Related Health Issues
Even if your BMI doesn’t classify you as obese, you may still benefit from semaglutide if you have weight-related health issues, such as:
- High blood pressure
- Type 2 diabetes
- Sleep apnea
- Cardiovascular disease
- High cholesterol
3. Those Who Have Tried Other Weight Loss Methods
If you’ve struggled to lose weight through traditional methods like diet, exercise, or other weight-loss medications, semaglutide could offer the solution you’ve been seeking. It’s especially helpful for those who experience persistent hunger and cravings, which can derail other weight loss efforts.
4. People Committed to Long-Term Lifestyle Changes
Semaglutide works best when combined with dietary changes and increased physical activity. It’s not a standalone treatment, so it’s most effective for individuals ready to commit to long-term lifestyle adjustments for optimal results
How to Get Started with Semaglutide for Weight Loss
If you’re interested in using semaglutide for weight loss, here’s how to begin:
1. Consult with a Qualified Healthcare Provider
The first step is to schedule a consultation with a healthcare provider. This could be your primary care physician, an endocrinologist, or a weight loss specialist. Dr. Burns is proud to partner with Jenni Crayton, FNP-C, a nurse practitioner specializing in medical weight loss. Ms. Crayton offers telemedicine as a convenient option for our patients.
During the consultation, your provider will assess your medical history, BMI, and any underlying health conditions to determine whether you’re a good candidate for semaglutide.
2. Prescription and Dosage
If approved, your healthcare provider will prescribe semaglutide, typically in the form of a once-weekly injection. Semaglutide dosages for weight loss start low and gradually increase over several weeks to minimize side effects. Your provider will instruct you on how to self-administer the medication at home.
- Initial Dosage: You’ll start with a lower dose, and for 16 to 20 weeks, your dosage will be gradually increased to reach the therapeutic level used for weight loss.
3. Lifestyle Adjustments
To maximize the effects of semaglutide, you’ll need to make specific lifestyle changes. This typically includes:
- Following A Reduced-calorie Diet: Your healthcare provider or nutritionist may help you develop a plan that works for you.
- Increasing Physical Activity: Regular exercise can help amplify weight loss results.
- Behavioral Counseling: Some clinics may offer support through behavioral therapy, helping you adopt new habits and stick to your weight loss plan.
4. Monitoring Progress
As with any medical weight loss program, you must check in regularly with your healthcare provider. They will monitor your progress, adjust your dosage if needed, and track potential side effects. Common side effects include nausea, diarrhea, or constipation, but these often diminish as your body adjusts to the medication.
Results and Success Rates with Semaglutide
Semaglutide has shown remarkable success in clinical trials for weight loss. In the STEP clinical trials, participants taking semaglutide lost an average of 15-20% of their body weight over 68 weeks, compared to a 2.4% weight loss in those who received a placebo.
Additionally, most participants saw significant improvements in waist circumference, blood pressure, and blood sugar control, making semaglutide a powerful option not only for weight loss but for overall health improvement.
Conclusion
Semaglutide is an exciting and effective option for individuals looking to lose weight, especially if traditional methods haven’t worked. Its ability to suppress appetite, slow digestion, and improve insulin sensitivity makes it a comprehensive solution for managing obesity and weight-related health conditions.
If you believe you’re a good candidate for semaglutide, the best place to start is by consulting your healthcare provider. With the right guidance and commitment to a healthier lifestyle, semaglutide could be the key to achieving your long-term weight loss goals.
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